Opportunity Information: Apply for W81XWH 21 BCRP EOHS 2

The DoD Breast Cancer, Era of Hope Scholar Award (funding opportunity number W81XWH 21 BCRP EOHS 2) is a Department of Defense Breast Cancer Research Program opportunity administered by the U.S. Army Medical Research Acquisition Activity (USAMRAA). It is offered as either a grant or a cooperative agreement and falls under science and technology research and development (CFDA 12.420). The program is designed to invest in people rather than narrow project proposals, with a focus on identifying early-career investigators who have already shown exceptional promise and who are positioned to become influential leaders in breast cancer research.

At its core, this award targets individuals viewed as the "best and brightest" based on an unusual track record of creativity, vision, innovation, and productivity. The emphasis is on the Principal Investigator (PI) as a change-agent: reviewers are looking for evidence that the applicant consistently thinks beyond standard approaches, can challenge prevailing assumptions in their field, and is likely to make a distinctive, high-impact contribution toward ending breast cancer. While the application will describe a research plan, the defining feature is the PI's overarching scientific vision and the likelihood that the PI's ideas will shift the direction of breast cancer research rather than simply extend existing work.

A key point is that prior experience specifically in breast cancer research is not required. The opportunity explicitly welcomes applicants from other disciplines, especially those who can bring fresh concepts, tools, or perspectives into breast cancer research. Even so, the proposed work must be clearly focused on breast cancer, and the PI must commit at least 50 percent of their full-time professional effort during the award period to breast cancer research. That effort can be met by combining this award with other active support, as long as the overall time commitment to breast cancer research reaches the required level.

Collaboration is built into the program expectations. Applicants are encouraged to assemble a research team that includes the expertise needed to accomplish the goals and to demonstrate a real capacity for productive partnerships. In addition to scientific collaborators, the award requires meaningful consumer engagement: the PI's research team must include two or more breast cancer consumer advocates. These advocates must be breast cancer survivors who are actively involved in a breast cancer advocacy organization, and their advocacy role must be independent of their employment. They also cannot be employees of any organization participating in the application, which is intended to preserve their independence and objectivity.

The consumer advocates are not included as symbolic participants; they are expected to provide informed, ongoing input that strengthens the research and keeps it grounded in patient realities and impact. The opportunity notes that these advocates should have strong knowledge of current breast cancer issues and enough background and/or training in breast cancer research to contribute meaningfully. Their role is framed as helping evaluate the relevance, feasibility, and potential benefit of the work for people who have breast cancer or who are at risk of developing it, ensuring the research stays aligned with patient needs and priorities throughout the project.

From an administrative perspective, the opportunity was created on April 26, 2021, with an original closing date of September 14, 2021. Eligibility is listed as unrestricted (open to any type of entity), subject to any additional eligibility clarifications in the full announcement. The listing indicates an expectation of one award and shows an award ceiling of 0, which typically signals that applicants should rely on the full announcement for the actual funding limits and budget guidance rather than treating the listing field as a stated cap.

Overall, the Era of Hope Scholar Award is best understood as a prestigious, person-centered career acceleration mechanism within the DoD breast cancer portfolio. It seeks emerging scientific leaders with bold, unconventional ideas, a demonstrated ability to collaborate, and a clear commitment to dedicating substantial effort to breast cancer research, while also requiring authentic patient-advocate participation to keep the work focused on outcomes that matter to the breast cancer community.

  • The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Breast Cancer, Era of Hope Scholar Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
  • This funding opportunity was created on Apr 26, 2021.
  • Applicants must submit their applications by Sep 14, 2021. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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FAQs: DoD Breast Cancer, Era of Hope Scholar Award (W81XWH 21 BCRP EOHS 2)

What is the Era of Hope Scholar Award?

The DoD Breast Cancer, Era of Hope Scholar Award is a funding opportunity within the Department of Defense (DoD) Breast Cancer Research Program (BCRP). It is administered by the U.S. Army Medical Research Acquisition Activity (USAMRAA) and is designed to accelerate the careers of exceptional early-career investigators who are positioned to become influential leaders in breast cancer research.

What is the funding opportunity number for this award?

The funding opportunity number is W81XWH 21 BCRP EOHS 2.

Which agency administers this opportunity?

The opportunity is administered by the U.S. Army Medical Research Acquisition Activity (USAMRAA) under the Department of Defense Breast Cancer Research Program.

Is this funding offered as a grant or a cooperative agreement?

It may be offered as either a grant or a cooperative agreement.

What category or program area does this award fall under?

The award falls under science and technology research and development and is associated with CFDA 12.420.

What is the main goal of the Era of Hope Scholar Award?

The program is designed to invest in people rather than narrowly defined project proposals. The central goal is to identify early-career investigators who have already demonstrated exceptional promise and who are likely to become change-agents and leaders whose work can meaningfully shift the direction of breast cancer research.

Is the research plan the most important part of the application?

Based on the description provided, the defining feature is the Principal Investigator (PI), including the PI's overarching scientific vision and the likelihood that the PI's ideas will influence or shift the field. While the application will include a research plan, the emphasis is on the PI as a change-agent rather than on incremental extensions of existing work.

Who is the award intended for?

This award targets early-career investigators viewed as the "best and brightest" due to an unusual track record of creativity, vision, innovation, and productivity, with clear potential to make distinctive, high-impact contributions toward ending breast cancer.

Does the PI need prior experience in breast cancer research?

No. Prior experience specifically in breast cancer research is not required. Applicants from other disciplines are explicitly welcomed, particularly if they can bring new concepts, tools, or perspectives into breast cancer research.

If someone is coming from another discipline, does the work still need to be about breast cancer?

Yes. Even though breast cancer research experience is not required, the proposed work must be clearly focused on breast cancer.

How much time must the PI commit to breast cancer research during the award?

The PI must commit at least 50 percent of their full-time professional effort to breast cancer research during the award period.

Can the 50 percent effort requirement be met by combining this award with other support?

Yes. The 50 percent commitment can be met by combining this award with other active support, as long as the total time devoted to breast cancer research reaches the required level.

What does the program mean by investing in the PI as a "change-agent"?

Reviewers are looking for evidence that the PI consistently thinks beyond standard approaches, can challenge prevailing assumptions, and is likely to make a distinctive contribution that shifts the direction of breast cancer research rather than simply extending existing work.

Is collaboration encouraged or required?

Collaboration is built into the program expectations. Applicants are encouraged to assemble a research team with the expertise needed to accomplish the goals and to show a real capacity for productive partnerships.

Is consumer engagement required?

Yes. The PI's research team must include meaningful consumer engagement, including two or more breast cancer consumer advocates.

How many consumer advocates are required on the research team?

Two or more breast cancer consumer advocates are required.

Who qualifies as a breast cancer consumer advocate for this award?

Consumer advocates must be breast cancer survivors who are actively involved in a breast cancer advocacy organization. Their advocacy role must be independent of their employment.

Are there independence requirements for the consumer advocates?

Yes. Consumer advocates cannot be employees of any organization participating in the application. This is intended to preserve independence and objectivity.

Are consumer advocates included just to satisfy a requirement?

No. The opportunity describes consumer advocates as expected to provide informed, ongoing input that strengthens the research and keeps it grounded in patient realities and impact.

What kind of contributions are consumer advocates expected to make?

They are expected to help evaluate the relevance, feasibility, and potential benefit of the work for people who have breast cancer or who are at risk of developing it, and to help ensure the research remains aligned with patient needs and priorities throughout the project.

Do the consumer advocates need knowledge of breast cancer research?

Yes. The description indicates they should have strong knowledge of current breast cancer issues and enough background and/or training in breast cancer research to contribute meaningfully.

What is the listed eligibility for applicants?

Eligibility is listed as unrestricted (open to any type of entity), subject to any additional eligibility clarifications in the full announcement.

When was this opportunity created and when did it originally close?

The opportunity was created on April 26, 2021, and the original closing date was September 14, 2021.

How many awards are expected?

The listing indicates an expectation of one award.

Is there a maximum (ceiling) award amount shown?

The listing shows an award ceiling of 0. This typically indicates that applicants should rely on the full announcement for actual funding limits and budget guidance rather than treating the listing field as a stated cap.

What is the overall purpose of this award within the DoD breast cancer portfolio?

It is best understood as a prestigious, person-centered career acceleration mechanism that supports emerging scientific leaders with bold, unconventional ideas, a demonstrated ability to collaborate, and a clear commitment to dedicating substantial effort to breast cancer research, while also requiring authentic patient-advocate participation.

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