Opportunity Information: Apply for HT942526LRPTVA
The DoW Lupus Transformative Vision Award (Funding Opportunity Number HT942526LRPTVA) is a discretionary grant from the Department of the Army (USAMRAA) under CFDA 12.420 that funds science and technology research focused on lupus. The core purpose of this mechanism is to support interventional research that can produce a near-term, measurable improvement in the health-related quality of life of people living with lupus. Projects can intervene at the level of the individual (for example, patient-centered interventions, care strategies, or therapeutic approaches tested in humans) and/or at the health care system level (for example, interventions that change care delivery, access, coordination, adherence support, or other system processes that directly affect patient quality of life). A key requirement is that the proposed work must align with at least one of the FY26 Lupus Research Program Transformative Vision Award focus areas, meaning applicants need to clearly map their aims and outcomes to the program-defined priorities.
This opportunity is designed to support research that is practical and impact-driven rather than exploratory work that may take many years to translate. Clinical trials are permitted under this award, which signals that the program is open to rigorous human-subjects testing when it is the right path to near-term quality-of-life gains. At the same time, animal studies are explicitly not allowed, so the research plan must be centered on human-based approaches, real-world care settings, clinical implementation strategies, or other non-animal methods that directly relate to improving patient experiences and outcomes.
Several distinctive application features shape how teams should prepare. Applicants must include preliminary data, so proposals need to be supported by existing evidence that the intervention is feasible and has a credible rationale for improving quality of life soon after implementation. In addition, every application must include at least one lupus consumer advocate as part of the research team, reinforcing that the work should be informed by lived experience and oriented toward outcomes that matter to patients. The award also supports collaborative leadership: teams may propose up to three Principal Investigators. The process is structured so that one initiating PI submits the pre-application, but all PIs must submit full applications. Partnering PI applications are abbreviated and cover the distinct components of the shared project they will lead. Because the applications are linked, the program notes that the entire set of associated applications may be withdrawn if the initiating or any partnering application is rejected or administratively withdrawn, so coordination across PIs and institutional submissions is important.
There are also limits on how investigators can participate across the broader FY26 Lupus Research Program portfolio. An individual may be listed as PI on only one application per LRP award mechanism (Idea Award, Impact Award, Transformative Vision Development Award, and Transformative Vision Award), with a maximum of four total PI applications across the FY26 LRP if applying to multiple mechanisms. Eligibility is listed as unrestricted, and the original closing date is August 24, 2026. The opportunity indicates an expectation of one award, and while an award ceiling is referenced, a specific maximum amount is not provided in the supplied listing, so applicants would need to confirm budget limits and other administrative details in the full announcement materials and associated program guidance.Apply for HT942526LRPTVA
- The Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoW Lupus, Transformative Vision Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
- This funding opportunity was created on 2026-05-05.
- Applicants must submit their applications by 2026-08-24. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Unrestricted.
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FAQs: DoW Lupus Transformative Vision Award (HT942526LRPTVA)
What is the DoW Lupus Transformative Vision Award?
The DoW Lupus Transformative Vision Award (Funding Opportunity Number HT942526LRPTVA) is a discretionary research grant mechanism offered through the Department of the Army (USAMRAA) under CFDA 12.420. It funds science and technology research focused on lupus, with an emphasis on practical, impact-driven work.
What is the main goal of this funding opportunity?
The core purpose is to support interventional research that can produce a near-term, measurable improvement in the health-related quality of life of people living with lupus.
What kinds of research projects are a fit for this award?
Projects should be interventional and designed to deliver near-term quality-of-life improvements. Interventions can target individuals (such as patient-centered interventions, care strategies, or therapeutic approaches tested in humans) and/or health care systems (such as improving care delivery, access, coordination, adherence support, or other system processes that directly affect patient quality of life).
Does the program require alignment with specific focus areas?
Yes. A key requirement is that the proposed work must align with at least one of the FY26 Lupus Research Program Transformative Vision Award focus areas. Applicants need to clearly map their aims and expected outcomes to the program-defined priorities.
Is this opportunity intended for exploratory or early-stage research?
No. This mechanism is positioned to support research that is practical and impact-driven, rather than exploratory work that may take many years to translate into real-world benefit.
Are clinical trials allowed under this award?
Yes. Clinical trials are permitted, indicating the program is open to rigorous human-subjects testing when it supports near-term improvements in quality of life.
Are animal studies allowed?
No. Animal studies are explicitly not allowed. Research plans must be centered on human-based approaches, real-world care settings, clinical implementation strategies, or other non-animal methods tied to improving patient experiences and outcomes.
Is preliminary data required?
Yes. Applications must include preliminary data. Proposals should be supported by existing evidence that the intervention is feasible and that there is a credible rationale for improving quality of life soon after implementation.
Is a lupus consumer advocate required on the research team?
Yes. Every application must include at least one lupus consumer advocate as part of the research team, reinforcing that the work should be informed by lived experience and focused on outcomes that matter to patients.
How many Principal Investigators (PIs) are allowed?
Teams may propose up to three Principal Investigators, supporting collaborative leadership structures.
How does the submission process work when there are multiple PIs?
One initiating PI submits the pre-application. For the full application stage, all PIs must submit full applications. Partnering PI applications are abbreviated and should cover the distinct components of the shared project they will lead.
Are the initiating PI and partnering PI applications linked?
Yes. The applications are linked, and the program notes that the entire set of associated applications may be withdrawn if the initiating or any partnering application is rejected or administratively withdrawn. This makes coordination across PIs and institutional submissions especially important.
Are there limits on how many applications a person can submit as PI?
Yes. An individual may be listed as PI on only one application per LRP award mechanism (Idea Award, Impact Award, Transformative Vision Development Award, and Transformative Vision Award). Across all FY26 LRP mechanisms, an individual may submit a maximum of four total PI applications if applying to multiple mechanisms.
Who is eligible to apply?
Eligibility is listed as unrestricted in the provided information.
What is the closing date for this opportunity?
The original closing date provided is August 24, 2026.
How many awards does the program expect to make?
The opportunity indicates an expectation of one award.
Is there a maximum award amount (budget ceiling)?
An award ceiling is referenced, but a specific maximum amount is not provided in the supplied listing. Applicants would need to confirm budget limits and related administrative details in the full announcement materials and associated program guidance.
What should applicants do if they need budget or administrative details not shown here?
Because the supplied summary does not include the specific award ceiling amount and may not include all administrative requirements, applicants should consult the full announcement materials and any associated program guidance to confirm budget limits and other details.
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| DoW Lupus, Idea Award Apply for HT942526LRPIA Funding Number: HT942526LRPIA Agency: Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoW Lupus, Transformative Vision Development Award Apply for HT942526LRPTVDA Funding Number: HT942526LRPTVDA Agency: Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoW Lupus, Impact Award Apply for HT942526LRPIPA Funding Number: HT942526LRPIPA Agency: Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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