Opportunity Information: Apply for CDC RFA GH21 2120

This funding opportunity, titled "Strengthening Public Health Capacity, Strategic Information Systems, and Community Engagement through Cooperation and Support Services from the Joint United Nations Programme on HIV/AIDS (UNAIDS) under PEPFAR," is a CDC cooperative agreement (Funding Opportunity Number: CDC RFA GH21 2120; CFDA: 93.067) designed to support global HIV efforts aligned with PEPFAR and UNAIDS priorities. It sits within the health funding activity category and is administered by the Department of Health and Human Services, Centers for Disease Control and Prevention, Center for Global Health (CDC-CGH). The NOFO was posted on February 18, 2021, with an original application deadline of April 19, 2021 (applications due by 11:59 p.m. ET). CDC anticipated making one award.

The central purpose of the opportunity is to strengthen the global HIV response as international resources and programming expectations shift toward durable, sustainable epidemic control and the longer-term goal of ending the HIV epidemic by 2030. The NOFO emphasizes that achieving this goal depends on concentrating efforts where they will have the greatest impact: delivering evidence-based interventions to populations at highest risk, guided by high-quality data. In practical terms, the opportunity is meant to help PEPFAR-supported countries and regions, as well as the broader global community, better understand the true scope and geographic distribution of HIV, track how the epidemic is changing over time, and use that information to make smarter and faster decisions about where to focus prevention, testing, treatment, and support services.

A major theme is the strategic use of data and strategic information systems. The NOFO highlights a data-driven approach sometimes described as doing the right things, in the right places, at the right time. That means improving the ability of countries and partners to measure the epidemic accurately, identify gaps and hot spots, and predict emerging trends so programs can be adapted before losses in progress occur. The intention is not only to collect data, but to strengthen the systems, methods, and analytic capacity needed to translate data into actionable guidance for national programs and implementing partners.

Another major focus is collaboration that leverages the comparative strengths of CDC and UNAIDS. Through this cooperative agreement structure, CDC anticipated working closely with UNAIDS to provide technical assistance and guidance across multiple technical areas that support PEPFAR goals. While the NOFO is broad, its unifying aim is to improve the evidence base behind the global HIV/AIDS response and to ensure that investments are directed for maximum impact, ultimately accelerating progress toward epidemic control and an end to AIDS by 2030.

Community engagement is also explicitly prioritized, particularly through improving and enhancing community-led networks. The opportunity recognizes that community-led approaches play a key role in reaching people most affected by HIV, addressing barriers like stigma and discrimination, improving service uptake and retention, and making programs more responsive to local needs. Strengthening these networks is framed as a pathway to improving HIV services and, in turn, health outcomes for people living with HIV (PLHIV), including better continuity of care and stronger linkage between services and the communities they are meant to serve.

In terms of funding, the NOFO includes the notable statement that the award ceiling for Year 1 is listed as 0 (none), while CDC simultaneously anticipated approximately $10,000,000 in total fiscal year funding for Year 1, contingent on the availability of funds. This indicates that while CDC projected substantial overall funding for the initiative, the ceiling field was not used as a traditional cap for Year 1 in the public listing. The instrument type is a cooperative agreement, which typically signals substantial federal involvement in collaboration, technical direction, and joint planning rather than a more hands-off grant structure.

Eligibility is described broadly as "Others," with direction to consult the additional eligibility text in the full notice for clarification. Overall, the opportunity is best understood as a targeted partnership mechanism to strengthen strategic information, public health capacity, and community engagement in PEPFAR-supported settings, using CDC and UNAIDS coordination to help countries pinpoint where the epidemic is concentrated, anticipate how it is changing, and improve service delivery and outcomes for PLHIV through more effective community-led and data-informed action.

  • The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Strengthening Public Health Capacity, Strategic Information Systems, and Community Engagement through Cooperation and Support Services from the Joint United Nations Programme on HIV/AIDS (UNAIDS) under PEPFAR" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
  • This funding opportunity was created on Feb 18, 2021.
  • Applicants must submit their applications by Apr 19, 2021 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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